An investigation by Johns Hopkins University has just been released on Medical Cannabis Laws and Opioid Analgesic Overdose Mortality in the United States from 1999 to 2010, resting in the latest release of JAMA’s Internal Medicine Online Magazine. The study was focused on the overdose mortality due to pharmaceuticals and pills mass-prescribed for chronic pain such as Vicodin and Percocet among others.
The researchers conducted a time series analysis of medical cannabis laws and state level death certificates in the United States from 1999 to 2010, all 50 states were included. The study found that in these years, states with medical cannabis laws had a 24.8% lower mean annual opioid (pain pill) overdose mortality rate compared to states without medical cannabis laws. The paper also shows that this effect over time lowers mortality year-by-year after implementation.
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In secondary analyses the findings remain similar, leaving strong conclusions that the medical cannabis laws are associated with significantly lower state level RX overdose mortality rates, and they recommend integration with public policies. The Endocannabinoid System is the most incredible modern science, and CBD is at the lead.
The Endocannabinoid System, (ECS) has many sub-systems specific to whatever is being focused on. The ECS physiology of seizures is different in specificity than the ECS physiology of diabetes or pain. Flagship medical facilities still ignore the dramatic benefits of CBD versus pharmaceuticals, and patients are less willing to undergo unnecessary treatments or go along with the provider’s scrip guesswork which rarely leads to a cure.
Success StoriesAmericans who are finding themselves at odds with the current medical industry must choose a quality set of supplements that will have maximum efficacy with the least amount of intake. TwinFalls Biotech is the maker of ArisiTol CBD Hemp-Oil Lozenges. They have expertly designed an all-natural alternative that is currently dominating the 40+ CBD market in the US, with over-the-counter retail sales spiking in September as regional Whole Foods markets and Hemp-Oil retailers generated superb market response.
The success of ArisiTol CBD Lozenges and other CBD products today lies in the Active itself. Cannabidiol, (CBD) is a naturally produced Cannabinoid, of which there are human biological counterparts, called Endocannabinoids; both are almost identical in form. Because of this, the human body gladly accepts this CBD Supplement as its own, allowing the Hemp-Oil derived CBD in ArisiTol act in its stead.
The Endocannabinoid system is a cellular lock and key system, using a receptor site lock, and a neuro-hormonal key. This system can up-regulate or down-regulate the neuro-hormonal flow in nerve transmission, as needed to maintain balance. As a result, cannabinoids can inhibit or uninhibit the nerve transmission of the entire section of the nervous system where cannabinoid receptor sites are found.
activeneurons1.jpgThe lock in this system is called a receptor site. There are 2 primary receptor sites of mention, called CB1 and CB2 receptor sites. The CB1 receptors are found primarily in the brain and the CB2 receptors are found throughout the body and brain. The keys in this system are called cannabinoids. Some of the primary and most researched cannabinoids are known as CBD, CBN, THC, CBG and CBC. Plant based cannabinoids are called Phytocannabinoids.
Cannabinoids positively modulate pathophysiologic responses. In other words, if the body is getting off course or out of balance, (sickness) in a negative pathological direction, cannabinoids will help to bring the body back into balance through activation of the Endocannabinoid system, restoring balance, resulting in health (wellness).
Even though its use is often advised by doctors, the painkiller acetaminophen — best known as Tylenol — does not help treat lower back pain, according to a new Australian study. The researchers found the drug was no more effective than a dummy pill for more than 1,600 people suffering from acute lower back pain.
Besides showing no effect in easing discomfort, the study also found the drug was no help in improving sleep woes tied to back pain, nor did it improve patients’ overall quality of life. Certainly, it is a good thing that people have nationwide access to quality CBD products like ArisiTol without having to use a doctor’s prescription, and awareness of CBD is becoming more commonplace among those over 40 who are in the highest benefit category.